Star Metro - Onco-Innovations Welcomes AstraZeneca's Interest in Founding Role in PROmAI - an Inka-led AI-Oncology Consortium

The PROmAI Consortium, initiated and led by Inka Health, is a collaborative initiative focused on advancing the development and validation of artificial intelligence methodologies to support improved prediction of oncology outcomes. Designed to address current limitations in translational modeling, particularly during the transition from early- to late-phase clinical development, the Consortium aims to bring together insights from pharmaceutical, data science, and clinical research communities. Inka Health is in active discussions with additional global pharmaceutical companies regarding potential participation in the Consortium and will provide further updates as progress is made.

By combining real-world and clinical trial data-including molecular, clinical, imaging, and other multimodal datasets-with emerging techniques in causal AI, the Consortium seeks to foster innovation in predictive modeling, enhance interpretability and reliability of results, and contribute to frameworks aligned with regulatory and payer expectations. Participating members will collaborate on the design and execution of research activities that support the broader goal of improving trust, transparency, and utility of AI-driven insights in oncology drug development. For Inka Health, this Consortium represents a strategic opportunity to lead the advancement of AI methodologies in oncology.

Through the EOI, AstraZeneca has expressed its intention to participate in the Consortium's exploratory phase, which will include joint planning discussions, early input into project direction, and strategic alignment around key use cases. The collaboration is expected to evolve over time, with the potential for broader participation in research publications, workshops, and future initiatives that advance the Consortium's scientific mission.

Onco-Innovations views this Expression of Interest as a strong validation of the PROmAI initiative's relevance and potential impact in the rapidly evolving field of oncology R&D. The Company remains committed to fostering cross-sector collaboration to unlock the transformative potential of artificial intelligence in clinical innovation.

"This is not just about proving that AI can work in oncology-it's about shaping how it should work in ways that matter to regulators, clinicians, and ultimately patients. Having AstraZeneca engage at this early stage signals a shared commitment to advancing practical, credible AI applications in one of medicine's most complex domains. As leaders in this space, we see PROmAI not only as a research initiative but as a foundation for setting standards around trust, utility, and translational impact in oncology-focused AI," stated Paul Arora, CEO of Inka Health.

About Inka Health

Inka Health is an AI-driven analytics company revolutionizing oncology research and drug development through advanced causal AI. Its proprietary platform, SynoGraph, leverages AI-powered causal inference to identify which cancer patients are most likely to respond to specific treatments, advancing precision medicine. By integrating diverse multimodal medical data-including genomics, transcriptomics, and proteomics-SynoGraph uncovers hidden insights that can optimize treatment decisions and clinical trial design. With this cutting-edge technology, Inka Health helps pharmaceutical companies accelerate drug deve0lopment, reduce trial failures, and bring life-saving therapies to market faster.

About Onco-Innovations Limited

Onco-Innovations is a Canadian-based company dedicated to cancer research and treatment, specializing in oncology. Onco's mission is to pursue the prevention and treatment of cancer through pioneering research and innovative solutions. The company has secured an exclusive worldwide license to patented technology that targets solid tumours.

ON BEHALF OF ONCO-INNOVATIONS LIMITED,

"Thomas O'Shaughnessy"
Chief Executive Officer

For more information, please contact:

Thomas O'Shaughnessy
Chief Executive Officer
Tel: + 1 888 261 8055
[email protected]

Forward-Looking Statements Caution. This news release contains forward-looking statements relating to the further development, potential commercialization and benefits of the Company's technologies, PROmAI, and the prospects of the Company, and the Company's business and plans generally, and other statements that are not historical facts. Forward-looking statements are often identified by terms such as "will", "may", "potential", "should", "anticipate", "expects" and similar expressions. All statements other than statements of historical fact, included in this release are forward-looking statements that involve risks and uncertainties. There can be no assurance that such statements will prove to be accurate and actual results and future events could differ materially from those anticipated in such statements. Important factors that could cause actual results to differ materially from the Company's expectations include the failure to further develop, prove out or commercialize its technologies, the failure to realize the anticipated benefits of PROmAI and other risks detailed from time to time in the filings made by the Company with securities regulators. The reader is cautioned that assumptions used in the preparation of any forward-looking information may prove to be incorrect. Events or circumstances may cause actual results to differ materially from those predicted, as a result of numerous known and unknown risks, uncertainties, and other factors, many of which are beyond the control of the Company. The reader is cautioned not to place undue reliance on any forward-looking information. Such information, although considered reasonable by management at the time of preparation, may prove to be incorrect and actual results may differ materially from those anticipated. Forward-looking statements contained in this news release are expressly qualified by this cautionary statement. The forward-looking statements contained in this news release are made as of the date of this news release and the Company will update or revise publicly any of the included forward-looking statements as expressly required by applicable law.

SOURCE: Onco-Innovations Limited

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